Options diagnosis. The biggest discovery in their new

Options to treat amyotrophic
lateral sclerosis are limited. Recent studies show that ALS and
tau-negative frontotemporal dementia (FTD) have the same neuropathology
associated with TDP-43 positive inclusions. Basically, TDP-43 can recruit ALS
pathogenesis. In a study where by Walker et al. (2015), when compared to normal
TDP-43, they found that phosphorylated TDP-43 leads to a definite ALS diagnosis.

The biggest discovery in their new mouse model they developed to further
understand TDP-43 phosphorylation, it was shown that even after degeneration of
neurons and motor abilities, the removal of cytoplasmic TDP-43 and return of
nuclear TDP-43 led to neuron preservation and recovery of function. 

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